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Pediatric Neurology Feb 2023In the Division of Pediatric Neurology at the University Medical Center Göttingen we observed that many patients with Bell palsy are overweight or obese. To evaluate...
BACKGROUND
In the Division of Pediatric Neurology at the University Medical Center Göttingen we observed that many patients with Bell palsy are overweight or obese. To evaluate whether overweight and obesity are associated with increased risk of Bell palsy in children we conducted this single-centered retrospective study by performing a database search for International Classification of Diseases (ICD)-10 primary and secondary diagnosis of G51.0 (facial nerve palsy) between January 1, 2010, and December 31, 2020.
METHODS
For risk assessment, patients' body mass indices (BMIs) were compared with BMI data of controls from a nationwide child health survey.
RESULTS
In total, 202 patients with peripheral facial nerve palsies (pFPs) were included, of which nearly half were classified as Bell palsies; 38% and 24% of the patients with Bell palsy and pFP had a BMI above the 90th percentile, respectively. High BMI was associated with statistically increased odds of Bell palsy in the group of overweight and obese patients (BMI >90th percentile; odds ratio [OR], 2.42; 95% confidence interval [CI], 1.6 to 3.8; P < 0.001) and solely obese patients (BMI >97th percentile; OR, 2.43; 95% CI, 1.4 to 4.3; P = 0.003).
CONCLUSIONS
We could confirm our observation that overweight and obesity are associated with increased risk of Bell palsy in children.
Topics: Child; Humans; Overweight; Bell Palsy; Retrospective Studies; Obesity; Risk Assessment; Body Mass Index; Facial Paralysis; Pediatric Obesity
PubMed: 36508882
DOI: 10.1016/j.pediatrneurol.2022.11.007 -
BMJ (Clinical Research Ed.) Jun 2005
Review
Topics: Adult; Bell Palsy; Humans; Male; Physical Examination; Referral and Consultation
PubMed: 15947400
DOI: 10.1136/bmj.330.7504.1374 -
European Annals of Otorhinolaryngology,... Dec 2016
Topics: Aged; Bell Palsy; Breast Neoplasms; Female; Humans; Petrous Bone; Skull Neoplasms
PubMed: 27344096
DOI: 10.1016/j.anorl.2016.06.002 -
Neurologia Jul 2023To estimate the pooled incidence of Bell's palsy after COVID-19 vaccination. (Review)
Review
OBJECTIVE
To estimate the pooled incidence of Bell's palsy after COVID-19 vaccination.
METHODS
PubMed, Scopus, EMBASE, Web of Science, and Google Scholar were searched by 2 independent researchers. We also searched the grey literature including references of the references and conference abstracts. We extracted data regarding the total number of participants, first author, publication year, the country of origin, sex, type of vaccines, and the number of patients who developed Bell's palsy after COVID-19 vaccination.
RESULTS
The literature search revealed 370 articles, subsequently deleting duplicates 227 remained. After careful evaluation of the full texts, 20 articles remained for meta-analysis. The most commonly administered vaccines were Pfizer followed by Moderna. In total, 4.54e+07 individuals received vaccines against COVID-19, and 1739 cases developed Bell's palsy. In nine studies, controls (individuals without vaccination) were enrolled. The total number of controls was 1 809 069, of whom 203 developed Bell's palsy. The incidence of Bell's palsy after COVID-19 vaccines was ignorable. The odds of developing Bell's palsy after COVID-19 vaccines was 1.02 (95% CI: 0.79-1.32) (I2 = 74.8%, P < .001).
CONCLUSION
The results of this systematic review and meta-analysis show that the incidence of peripheral facial palsy after COVID-19 vaccination is ignorable and vaccination does not increase the risk of developing Bell's palsy. Maybe, Bell's palsy is a presenting symptom of a more severe form of COVID-19, so clinicians must be aware of this.
PubMed: 37433426
DOI: 10.1016/j.nrleng.2023.06.002 -
The Western Journal of Medicine Oct 2000
Topics: Acyclovir; Antiviral Agents; Bell Palsy; Evidence-Based Medicine; Glucocorticoids; Humans; Prednisone; Randomized Controlled Trials as Topic
PubMed: 11017995
DOI: 10.1136/ewjm.173.4.266 -
British Medical Journal May 1956
Topics: Bell Palsy; Face; Facial Paralysis; Paralysis
PubMed: 13316077
DOI: 10.1136/bmj.1.4975.1087 -
American Family Physician Oct 2011
PubMed: 22010774
DOI: No ID Found -
CMAJ : Canadian Medical Association... Apr 2013
Topics: Acupuncture Therapy; Bell Palsy; Female; Humans; Male
PubMed: 23529967
DOI: 10.1503/cmaj.130319 -
The Lancet. Infectious Diseases Sep 2021
Topics: Bell Palsy; COVID-19; COVID-19 Vaccines; Humans; Influenza Vaccines; SARS-CoV-2
PubMed: 34111409
DOI: 10.1016/S1473-3099(21)00273-5 -
Medical Science Monitor : International... Mar 2023BACKGROUND The present study aimed to investigate the relationship between Bell's palsy (BP) and cerebral white matter lesions (CWMLs) on brain gadolinium-enhanced...
BACKGROUND The present study aimed to investigate the relationship between Bell's palsy (BP) and cerebral white matter lesions (CWMLs) on brain gadolinium-enhanced magnetic resonance imaging (MRI). MATERIAL AND METHODS The study included 51 patients who were diagnosed with BP and a control group of 40 individuals who underwent brain MRI for investigation of headache etiology. The brain MRIs of the patients were reviewed with respect to CWMLs. CWMLs were compared between the 2 groups, and within the BP group, the correlation between CWML and House-Brackmann (HB) facial nerve palsy grade was investigated as well. RESULTS There were significantly more CWMLs in the BP group than in the control group (P=0.003). There was a statistically significant difference between the HB subgroups in terms of absence/presence of CWMLs (P=0.040). Within the BP patient group, there were significantly more CWMLs in the HB grade 5 and 6 groups compared with the HB grade 2 group (P=0.025 and P=0.042, respectively). Overall, the CWML scores correlated positively with HB grade. When absence/presence of CWMLs was compared between the BP and control groups in only patients aged <50 years, there was a statistically significant difference between the groups (P=0.008). No statistically significant difference in absence/presence of CWMLs, however, was found between the BP and control groups when only patients age ≥50 years were considered (P=0.809). CONCLUSIONS We showed that as the severity of Bell's palsy increased, CWMLs increased and there was an association between CWMLs and BP. Microvascular ischemic pathologies may be among the most important factors in the etiopathogenesis of BP.
Topics: Humans; Bell Palsy; White Matter; Magnetic Resonance Imaging; Head; Vascular Diseases
PubMed: 36941767
DOI: 10.12659/MSM.939723